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  • Title: Design, multicomponent synthesis, and bioactivities of novel neonicotinoid analogues with 1,4-dihydropyridine scaffold.
    Author: Zhang W, Yang X, Chen W, Xu X, Li L, Zhai H, Li Z.
    Journal: J Agric Food Chem; 2010 Mar 10; 58(5):2741-5. PubMed ID: 20000775.
    Abstract:
    Novel neonicotinoid analogues bearing a 1,4-dihydropridine scaffold were designed and synthesized by multicomponent reactions (MCRs) to enhance pi-pi stacking. The synthesized compounds were identified by (1)H NMR, (13)C NMR, high-resolution mass spectroscopy, and elemental analysis. Bioassay tests showed that some of them exhibited high insecticidal activities against pea aphid ( Aphis craccivora ).
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