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  • Title: Bilateral acute angle-closure glaucoma in a migraine patient receiving topiramate: a case report.
    Author: Cole KL, Wang EE, Aronwald RM.
    Journal: J Emerg Med; 2012 Aug; 43(2):e89-91. PubMed ID: 20005660.
    Abstract:
    BACKGROUND: Patients with migraine headaches are frequently prescribed topiramate to treat their condition. CASE REPORT: We present a case of bilateral acute angle-closure glaucoma occurring 2 days after topiramate therapy was increased for symptoms related to migraine. CONCLUSION: Acute angle-closure glaucoma secondary to topiramate is an uncommon but serious adverse reaction that may result in severe morbidity such as permanent visual loss if not recognized in a timely manner. Treatment differs from primary acute angle-closure glaucoma in that discontinuation of topiramate is necessary for the glaucoma to resolve.
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