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  • Title: Antiviral flavonoids from Mosla scabra.
    Author: Wu Q, Yu C, Yan Y, Chen J, Zhang C, Wen X.
    Journal: Fitoterapia; 2010 Jul; 81(5):429-33. PubMed ID: 20006976.
    Abstract:
    An ethanolic extract and ethyl acetate fraction (EFMS) prepared from Mosla scabra showed potential inhibition against influenza viruses. The compounds isolated from EFMS were elucidated to be ursolic acid (1), 5-hydroxy-6,7-dimethoxyflavone (2), 5-hydroxy-7,8-dimethoxyflavone (3), apigenin (4) and acacetin (5) based on their spectral analysis. Compounds 2, 3, 4 and 5 showed significant anti-influenza viruses activities. Compared with ribavirin, EFMS appeared to have similar efficacy against influenza viruses, was considered to be less toxic and may warrant further evaluation as a possible agent for the treatment of influenza.
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