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  • Title: [Compatibility chemistry of acid-alkaline pair medicine of Dahuang and Huangbai in Dahuang Xiaoshi decoction].
    Author: Pei M, Duan X, Pei X.
    Journal: Zhongguo Zhong Yao Za Zhi; 2009 Sep; 34(18):2312-5. PubMed ID: 20030076.
    Abstract:
    OBJECTIVE: To determine the change pattern of alkaline and acid components of Dahuang and Huangbai amoung different combinations in Dahuang Xiaoshi decotion. METHOD: The contents of anthraquinones and berberine were determined by HPLC in samples of Dahuang extracts, Huangbai extracts, Dahuang and Huangbai pair medicine extracts, and extracts of whole recipe. RESULT: The contents of anthraquinones and berberine were decreased with the changes of combinations: from component medicinal material alone to pair medicines, and to whole recipe. the change pattern was more apparent in water decoctions than in ethanol extracts. CONCLUSION: The contents of alkaline and acid components are changed with different extract methods and different combinations.
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