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  • Title: Cost-effectiveness of hepatitis A vaccination for individuals with chronic hepatitis C.
    Author: Chapko MK, Yee HS, Monto A, Dominitz JA.
    Journal: Vaccine; 2010 Feb 17; 28(7):1726-31. PubMed ID: 20044051.
    Abstract:
    The incidence of hepatitis A infection in the United States has decreased dramatically in recent years because of childhood immunization programs. A decision analysis of the cost-effectiveness of hepatitis A vaccination for adults with hepatitis C was conducted. No vaccination strategy is cost-effective for adults with hepatitis C using the recent lower anticipated hepatitis A incidence, private sector costs, and a cost-effectiveness criterion of $100,000/QALY. Vaccination is cost-effective only for individuals who have cleared the hepatitis C virus when Department of Veterans Affairs costs are used. The recommendation to vaccinate adults with hepatitis C against hepatitis A should be reconsidered.
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