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  • Title: Smoking behavior in women with locally advanced cervical carcinoma: a Gynecologic Oncology Group study.
    Author: Waggoner SE, Darcy KM, Tian C, Lanciano R.
    Journal: Am J Obstet Gynecol; 2010 Mar; 202(3):283.e1-7. PubMed ID: 20044066.
    Abstract:
    OBJECTIVE: The purpose of this study was to assess cigarette use and environmental smoke exposure in women with cervical cancer. STUDY DESIGN: Smoking behavior was recorded prospectively in a clinical trial of women with locally advanced cervical carcinoma. RESULTS: Of 315 participants, 133 women (42%) were current smokers; 72 women (23%) were former smokers, and 110 women (35%) were never smokers. Current smokers began smoking earlier (16 vs 18 years; P = .009), for more years (29 vs 24 years; P = .005), and in greater amounts (20 vs 11 cigarettes/d; P < .001) than former smokers. Active smokers lived more often with another smoker (63.3%), compared with former smokers (35.0%; P < .001) or never-smokers (28.7%; P < .001). Agreement between self-report and urine cotinine level was high (kappa = 0.872; P < .001). A significant decrease in cotinine level during treatment occurred in 5.2% of current smokers. CONCLUSION: Prevalence of smoking and tobacco consumption was twice that of the North American female population. Few smokers quit or decreased consumption during treatment.
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