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  • Title: PAF-acether in AK-5 tumour cells.
    Author: Marathe GK, Krishnakantha TP, D'Souza CJ.
    Journal: Cell Biol Int Rep; 1991 Jan; 15(1):85-90. PubMed ID: 2004428.
    Abstract:
    PAF-Acether fraction derived from stimulated AK-5 tumour cells, aggregated human platelets. The platelet aggregating ability increased linearly with increasing concentration of the stimulant, calcium ionophore A23187, and reached a maximum at 6 microM in 25 minutes. This factor had biological and chemical properties identical to authentic PAF-acether. Our results demonstrate that, although PAF-acether is produced mainly from pro-inflammatory cells, it appears to be produced even in tumour cells.
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