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  • Title: Acceptability of a non-woven device for vaginal drug delivery of microbicides or other active agents.
    Author: Joanis CL, Hart CW.
    Journal: AIDS Behav; 2010 Jun; 14(3):600-6. PubMed ID: 20049522.
    Abstract:
    Vaginal microbicides could reduce incidence of HIV. However, the current method of delivering gel formulations (standard applicator) can result in acceptability concerns/issues. This study evaluated the concept of using a non-woven textile material (modified tampon) for vaginal drug delivery. The study was nested within a Phase I randomized safety trial of lime juice concentrations used intra-vaginally. Of 47 women completing the safety trial, 16 were interviewed about their experiences. Overall, women found the concept of non-woven materials for vaginal drug delivery acceptable for use in delivering yeast medications (13 of 16) and STI/HIV preventives (10 of 16).
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