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  • Title: [Role of the medial hypothalamus in regulating the pituitary-adrenocortical system].
    Author: Filaretov AA, Rakitskaia VV.
    Journal: Fiziol Zh SSSR Im I M Sechenova; 1977 Oct; 63(10):1407-10. PubMed ID: 200496.
    Abstract:
    In unrestrained rabbits, inhibition of ACTH release as determined by changes in plasma levels of corticosteroids, followed electrolytic lesion of the dorso-and ventromedia nuclei of the hypothalamus. Electric stimulation of the dorsal midbrain tegmentum had activated ACTH prior to lesion; after the lesion of the dorso-and ventromedial nuclei the stimulation produced no response. The dorso-and ventromedial nuclei of the hypothalamus are essential for basal and induced secretion of the ACTH.
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