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  • Title: Multicomponent reaction discovery: three-component synthesis of spirooxindoles.
    Author: Liang B, Kalidindi S, Porco JA, Stephenson CR.
    Journal: Org Lett; 2010 Feb 05; 12(3):572-5. PubMed ID: 20050598.
    Abstract:
    The Lewis acid-catalyzed, three-component reaction of isatin and two 1,3-dicarbonyl compounds is reported. Reactions proceed with high efficiency under mild reaction conditions and with good functional group tolerance to afford spirooxindole pyranochromenedione derivatives.
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