These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Deep white matter volume loss and social reintegration after traumatic brain injury in children.
    Author: Gale SD, Prigatano GP.
    Journal: J Head Trauma Rehabil; 2010; 25(1):15-22. PubMed ID: 20051899.
    Abstract:
    OBJECTIVE: To explore whether children judged by their parents as showing an "excellent" or "complete" social reintegration after pediatric traumatic brain injury have less white matter volume (WMV) loss and better neuropsychological test scores than children who do not achieve this same level of reintegration. SETTING: Primary-care hospital/medical center. PARTICIPANTS: Twenty-eight children with post-acute traumatic brain injury evaluated as outpatients. MEASURES: Parental ratings of overall social reintegration, neuropsychological test performance, and voxel-based morphometry analysis of brain WMV loss. RESULTS: In addition to showing worse neuropsychological test performance, children judged not to make a complete or excellent social reintegration had greater WMV loss, particularly within the corpus callosum. WMV loss in the corpus callosum correlated with the child's Wechsler Intelligence Scale for Children-Fourth Edition (WISC-IV) Full Scale IQ (rho = .677, P = .000) and parental ratings of level of social integration (rho = .415, P = .028). Admitting Glasgow Coma Scale scores, mother's level of education, WISC-IV Processing Speed Index scores, and WMV loss in the region of the corpus callosum significantly contributed to parental ratings of a child's level of social reintegration. CONCLUSIONS: Preliminary findings suggested that diffuse WMV loss, particularly in deep brain regions (eg, corpus callosum), may relate to the child's long-term psychosocial outcome as viewed from the parents' perspective.
    [Abstract] [Full Text] [Related] [New Search]