These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: An analysis pipeline for the inference of protein-protein interaction networks.
    Author: Taylor RC, Singhal M, Daly DS, Gilmore J, Cannon WR, Domico K, White AM, Auberry DL, Auberry KJ, Hooker BS, Hurst G, McDermott JE, McDonald WH, Pelletier DA, Schmoyer D, Wiley HS.
    Journal: Int J Data Min Bioinform; 2009; 3(4):409-30. PubMed ID: 20052905.
    Abstract:
    We present a platform for the reconstruction of protein-protein interaction networks inferred from Mass Spectrometry (MS) bait-prey data. The Software Environment for Biological Network Inference (SEBINI), an environment for the deployment of network inference algorithms that use high-throughput data, forms the platform core. Among the many algorithms available in SEBINI is the Bayesian Estimator of Probabilities of Protein-Protein Associations (BEPro3) algorithm, which is used to infer interaction networks from such MS affinity isolation data. Also, the pipeline incorporates the Collective Analysis of Biological Interaction Networks (CABIN) software. We have thus created a structured workflow for protein-protein network inference and supplemental analysis.
    [Abstract] [Full Text] [Related] [New Search]