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  • Title: [Immune algorithm: a new chemometrics tool for resolution of multicomponent overlapping chromatographic signals].
    Author: Shao X, Liu Z, Cai W.
    Journal: Se Pu; 2009 Sep; 27(5):648-54. PubMed ID: 20073200.
    Abstract:
    Chromatography and related hyphenated techniques have been one of the most important tools for complex sample analysis. Although advances in equipments and experimental techniques have been achieved, overlapping chromatographic peaks are still unavoidable when complex samples are analyzed. Chemometrics, which uses mathematical tools to deal with the overlapping analytical signals, provides alternative approaches for the resolution of overlapping chromatographic signals. In this review, the advances in the studies of immune algorithms (IAs) are summarized with the applications of the methods in the resolution of multicomponent overlapping chromatographic signals.
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