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  • Title: Paltolides A--C, anabaenopeptin-type peptides from the palau sponge Theonella swinhoei.
    Author: Plaza A, Keffer JL, Lloyd JR, Colin PL, Bewley CA.
    Journal: J Nat Prod; 2010 Mar 26; 73(3):485-8. PubMed ID: 20078073.
    Abstract:
    Three new anabaenopeptin-like peptides, named paltolides A-C, were isolated from a deep-water specimen of the marine sponge Theonella swinhoei from Palau. Paltolides belong to a rare subgroup of sponge-derived anabaenopeptins that have in common a C-terminal tryptophan residue linked to the epsilon-amine of a lysine bearing a d configuration. The structures of paltolides A-C were determined by NMR and tandem MS techniques. Paltolide A is the first anabaenopeptin structure where a non-N-methylated amino acid precedes the C-terminal residue.
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