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  • Title: New neo-clerodane diterpenoids from Scutellaria barbata with cytotoxic activities.
    Author: Dai SJ, Qu GW, Yu QY, Zhang DW, Li GS.
    Journal: Fitoterapia; 2010 Oct; 81(7):737-41. PubMed ID: 20079810.
    Abstract:
    Two new neo-clerodane diterpenoids have been isolated from the whole plant of Scutellaria barbata D. Don, and their structures were established by detailed spectral analyses as scutehenanine H (1) and 6-(2,3-epoxy-2-isopropyl-n-propoxyl)barbatin C (2). In vitro, the isolated two new compounds showed significant cytotoxic activities against three human cancer lines, and gave IC(50) values in the range OF 2.0-4.2 μΜ.
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