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  • Title: Neuroleptic malignant syndrome. When levodopa withdrawal is the cause.
    Author: Rainer C, Scheinost NA, Lefeber EJ.
    Journal: Postgrad Med; 1991 Apr; 89(5):175-8, 180. PubMed ID: 2008397.
    Abstract:
    Neuroleptic malignant syndrome has been described in patients receiving dopamine antagonists and in a few patients after withdrawal of dopaminergic antiparkinson therapy. Complications affect almost all organ systems and can be life-threatening. Most patients have fever, altered level of consciousness, bradykinesia, and rigidity. Treatment includes withdrawal of the causative agent and supportive therapy for complications. When withdrawal of a dopaminergic medication is the suspected cause, the agent should be reinstated.
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