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  • Title: [A dose-effect relationship study for the frequency of binuclear cells with micronuclei in a human lymphocyte culture after gamma irradiation].
    Author: Ankina MA, Mikhaĭlova GF.
    Journal: Radiobiologiia; 1991; 31(1):71-6. PubMed ID: 2008526.
    Abstract:
    The method of the cytokinetic blocking was used to determine, in 18 healthy male donors aged 21-35 years, the frequency of binuclear cells with micronuclei that amounted to 1.1 +/- 0.2% (0.3-2.4%) on the average. The dependence of this parameter upon radiation dose (60Co-gamma radiation, 0.05 to 2 Gy) was a linear quadratic function and was described by the following regression equation: Yx = 0.76 + 5.76 D +/- 2.61 D2. With a dose of 0.05 Gy the frequency of binuclear cells with micronuclei exceeded significantly the control level.
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