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  • Title: Isolation of C11 cyclopentenones from two didemnid species, Lissoclinum sp. and Diplosoma sp.
    Author: Ogi T, Margiastuti P, Teruya T, Taira J, Suenaga K, Ueda K.
    Journal: Mar Drugs; 2009 Dec 17; 7(4):816-32. PubMed ID: 20098612.
    Abstract:
    A series of new C(11) cyclopentenones 1-7 was isolated, together with four known metabolites 9/10, 12 and 13, from the extract of the didemnid ascidian Lissoclinum sp. The other didemnid ascidian Diplosoma sp. contained didemnenones 1, 2 and 5, and five known metabolites 8-12. The structures of 1-7 were elucidated by spectroscopic analyses. Cytotoxicity of the isolated compounds was evaluated against three human cancer cell lines (HCT116, A431 and A549).
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