These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: An extension of secondary structure prediction towards the prediction of tertiary structure.
    Author: Garratt RC, Thornton JM, Taylor WR.
    Journal: FEBS Lett; 1991 Mar 11; 280(1):141-6. PubMed ID: 2009957.
    Abstract:
    Secondary structure prediction parameters and optimised decision constants for use with the method of Garnier et al. [(1978) J. Mol. Biol. 120, 97-120] have been derived for two new and distinct substates of beta-structure. These we term internal and external on the basis of their hydrogen bonding patterns. The profiles of the amino acids for several of the parameters are considerably different in the two substates. Predictions using the new parameters attempt to distinguish the strands at the core of the beta-sheet from those at its edges and so restrict the possible topologies in tertiary structure prediction. The potential application of these parameters is illustrated for the class of beta/alpha proteins.
    [Abstract] [Full Text] [Related] [New Search]