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  • Title: Drug treatment for chronic systolic heart failure.
    Author: Mörike K, Sindermann JR.
    Journal: Thorac Cardiovasc Surg; 2010 Feb; 58 Suppl 2():S170-2. PubMed ID: 20101534.
    Abstract:
    Drug treatment of chronic systolic heart failure usually includes angiotensin-converting enzyme inhibitor, or an angiotensin II receptor blocker, and a beta blocker, as prognostic benefit of these agents has been demonstrated in a large body of clinical trials. Depending on the stage of the disease and concomitant factors, an aldosterone antagonist and/or a digitalis glycoside may provide additional benefit. Most patients also receive a diuretic for symptomatic relief. Conversely, some drugs may precipitate or aggravate chronic systolic heart failure.
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