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  • Title: Allergy to nickel in orthodontic patients: clinical and histopathologic evaluation.
    Author: Pazzini CA, Pereira LJ, Marques LS, Generoso R, de Oliveira G.
    Journal: Gen Dent; 2010; 58(1):58-61. PubMed ID: 20129894.
    Abstract:
    Adverse reactions stemming from the use of fixed and removable orthodontic appliances have been a cause for concern for both orthodontists and researchers in the health care field. Nickel often has been indicated as a biological sensitizer capable of causing short- and long-term reactions (Type IV immune response). This article addresses the clinical and diagnostic aspects of nickel-related reactions in orthodontic patients, based on the literature. A case report highlighting the periodontal, clinical, and histopathologic aspects of an allergic patient in orthodontic treatment is presented.
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