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  • Title: Airway responsiveness in atopic dermatitis.
    Author: Barker AF, Hirshman CA, D'Silva R, Hanifin JM.
    Journal: J Allergy Clin Immunol; 1991 Apr; 87(4):780-3. PubMed ID: 2013672.
    Abstract:
    Twelve of 123 patients with atopic dermatitis (AD) were screened by questionnaire and spirometry for the absence of smoking, hay fever, and respiratory disorders. Seven of these 12 patients had a positive methacholine challenge test. None of eight patients with another skin disorder, psoriasis, screened in a similar fashion, had a positive methacholine challenge. We conclude that hyperresponsive airways are a frequent finding in patients with AD and that similar mechanisms may account for the cutaneous physiologic and pharmacologic abnormalities that have been observed in AD.
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