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  • Title: Comparison of outcome in different types of stroke due to cerebral ischemia.
    Author: Osmani AH, Durrani RK, Ara J.
    Journal: J Coll Physicians Surg Pak; 2010 Jan; 20(1):42-6. PubMed ID: 20141692.
    Abstract:
    OBJECTIVE: To compare the outcome in different types of stroke according to cerebral ischemic region. STUDY DESIGN: Descriptive study. PLACE AND DURATION OF STUDY: Medical Unit-I (Ward 5), Jinnah Postgraduate Medical Centre, from June 2006 to April 2007. METHODOLOGY: A total of one hundred and forty seven patients of first ever cerebral infarcts admitted through emergency and medical OPD were included in the study and diagnosed on the basis of clinical findings and scan of brain. Detailed history and relevant examination was done. Causes of death during hospital stay were assessed. Discharged patients were followed-up in medical OPD and progress was monitored by modified Rankin scale at 1,3 and 6 months poststroke. RESULTS: One hundred and forty seven patients were studied. Their average age was 56.47+/-15.8 years. There were 80 (54.4%) males and 67 (45.6%) females. The stroke syndromes included partial anterior circulation stroke in 43 (29.25%), posterior circulation stroke in 30 (20.41%), total anterior circulation stroke (TACS) in 36 (24.49%) and lacunar stroke in 38 (25.85%). During their hospital stay, 45 (30.6%) patients expired and 102 (69.3%) were discharged.The total mortality rate was 36.05% at one month, 40.1% at third month and 43.5% at sixth month poststroke. Mortality was significantly high in patients with TACS (n-26, 72.2%, p-0.0001), Furthermore, at the time of incidence, 27.8%, 19.7% and 14.2% cases respectively were functionally dependent. Twenty five (65.7%) patients of lacunar stroke were independent (p=0.002) at the end of the sixth month poststroke. CONCLUSION: TACS had the worst outcome with the highest number of mortalities, whereas lacunar stroke had a better outcome, i.e. a majority of the patients were functionally independent by the end of 6 months.
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