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Title: Synthesis and biological evaluation of heteroanalogues of kotalanol and de-O-sulfonated kotalanol. Author: Mohan S, Jayakanthan K, Nasi R, Kuntz DA, Rose DR, Pinto BM. Journal: Org Lett; 2010 Mar 05; 12(5):1088-91. PubMed ID: 20143790. Abstract: The synthesis of nitrogen and selenium analogues of kotalanol and de-O-sulfonated kotalanol, naturally occurring sulfonium-ion glucosidase inhibitors isolated from Salacia reticulata, and their evaluation as glucosidase inhibitors against the N-terminal catalytic domain of human maltase glucoamylase (ntMGAM) are described.[Abstract] [Full Text] [Related] [New Search]