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  • Title: A seroprevalence study of poliovirus antibody against a collection of recombinant and non-recombinant poliovirus vaccine strains in the population of southern Greece.
    Author: Pliaka V, Ruether IG, Kyriakopoulou Z, Kioussi P, Plakokefalos E, Megalou M, Pratti A, Levidiotou-Stefanou S, Markoulatos P.
    Journal: Clin Microbiol Infect; 2010 Nov; 16(11):1672-5. PubMed ID: 20148919.
    Abstract:
    In this study, the serological status of the southern Greek population in the 1–10-year, 11–20-year, 21–30-year and 31–40-year age groups with regard to Sabin vaccine strains and a collection of 15 recombinant and four non-recombinant poliovirus vaccine strains was determined. For all three poliovirus types, the highest neutralization test (NT) titres were observed in the 1–10- year age group, indicating a good response to vaccination. In general, the serological status of the population of southern Greece with regard to poliovirus is better for types 1 and 2 than for type 3. The presence of the lowest NT titre in the 21– 30-year age group against poliovirus type 3 suggests the need for a booster dose of monovalent Sabin3 vaccine to ensure personal and herd immunity.
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