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  • Title: A new C29-sterol with a cyclopropane ring at C-25 and 26 from the Vietnamese marine sponge lanthella sp.
    Author: Tung NH, Van Minh C, Van Kiem P, Huong HT, Ha TT, Dat NT, Nhiem NX, Cuong NX, Hyun JH, Kang HK, Kim YH.
    Journal: Arch Pharm Res; 2009 Dec; 32(12):1695-8. PubMed ID: 20162396.
    Abstract:
    One new C(29) sterol with a cyclopropane ring at C-25 and C-26, aragusteroketal B (1), and aragusterol B (2) were isolated from the Vietnamese marine sponge Ianthella sp. Their structures were elucidated by extensive spectroscopic analyses. Both 1 and 2 showed moderate cytotoxic activity against MCF-7, SK-Hep-1, and HeLa cell lines with IC(50) in the range of 12.8-27.8 microM.
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