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  • Title: Solitary intra-abdominal Castleman's disease, hyaline vascular type: case report.
    Author: Al-Saleh N, Itty P, Kukawski P, Al-Khaldi K.
    Journal: Gulf J Oncolog; 2010 Jan; (7):53-6. PubMed ID: 20164010.
    Abstract:
    OBJECTIVE: To report a case of solitary intra-abdominal Castleman disease and highlight the importance of this entity to clinicians in the management of these patients. CASE PRESENTATION AND INTERVENTION: A 20 year old gentleman who presented with a recurrent intra-abdominal retroperitoneal mass. Previous biopsies obtained from a laparotomy showed Castleman disease- vascular hyaline type. Patient did not respond to chemotherapy and the mass was gradually increasing in size. Surgical intervention was the only option and the patient underwent complete resection of the retroperitoneal mass. Final histopathological examination confirmed the initial diagnosis of Castleman disease. CONCLUSION: Castleman's disease is a fairly rare benign tumor of lymphoid origin. It should be included in the list of differential diagnosis of retroperitoneal masses. Unicentric Castleman disease should be treated surgically when feasible and carries better prognosis compared to multicentric disease.
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