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  • Title: Synthesis and antimicrobial activities of novel biologically active heterocycles: 10h-phenothiazines, their ribofuranosides, and sulfone derivatives.
    Author: Dixit Y, Dixit R, Gautam N, Gautam DC.
    Journal: Nucleosides Nucleotides Nucleic Acids; 2009 Nov; 28(11):998-1006. PubMed ID: 20183568.
    Abstract:
    This article deals with the synthesis and antimicrobial activity of a series of novel substituted 10H-phenothiazines, their ribofuranosides, and sulfone derivatives. 10H-Phenothiazines were prepared by Smiles rearrangement. These prepared phenothiazines were used as the base to prepare ribofuranosides by treatment with sugar (1-O-acetyl-2,3,5-tri-O-benzoylribofuranose). Sulfone derivatives were prepared by the oxidation of 10H-phenothiazines. The structure of the synthesized compounds was established by elemental analysis and spectroscopic data.
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