These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Simple and versatile catalytic system for N-alkylation of sulfonamides with various alcohols.
    Author: Zhu M, Fujita K, Yamaguchi R.
    Journal: Org Lett; 2010 Mar 19; 12(6):1336-9. PubMed ID: 20184342.
    Abstract:
    A simple and versatile catalytic system for N-alkylation of sulfonamides with various alcohols based on a catalytic hydrogen transfer reaction has been developed under a low catalyst loading of [Cp*IrCl(2)](2) (0.050-1.5 mol %) in the presence of t-BuOK. A variety of N-alkylated sulfonamides were prepared in good to excellent yields. Mechanistic investigations revealed that the key catalytic species in the present system is a sulfonylimido-bridged unsaturated diiridium complex [(Cp*Ir)(2)(mu-NTs)(2)].
    [Abstract] [Full Text] [Related] [New Search]