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  • Title: Synthesis of naphtho[1,8-bc]pyran derivatives and related compounds through hydroxy group directed C-H bond cleavage under rhodium catalysis.
    Author: Mochida S, Shimizu M, Hirano K, Satoh T, Miura M.
    Journal: Chem Asian J; 2010 Apr 01; 5(4):847-51. PubMed ID: 20186908.
    Abstract:
    The straightforward and efficient synthesis of naphtho[1,8-bc]pyran derivatives and related polycyclic compounds is achieved by the rhodium-catalyzed oxidative coupling of 1-naphthols or other phenolic and alcoholic substrates with alkynes. In these annulation reactions, the hydroxy groups effectively act as the key function for the regioselective C-H bond cleavage.
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