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  • Title: HLA-D antigens and Paget's disease of bone.
    Author: Foldes J, Shamir S, Brautbar C, Schermann L, Menczel J.
    Journal: Clin Orthop Relat Res; 1991 May; (266):301-3. PubMed ID: 2019065.
    Abstract:
    HLA-A, -B, -C, -DR, and -DQ antigens were determined in 25 Ashkenazi Jews with Paget's disease of bone. HLA-DR2 was more frequent in the Pagetic patients compared with 57 healthy controls of the same ethnic origin. This finding concurs with a previous report and raises the possibility that HLA-DR2 may be associated with Paget's disease of bone, probably by predisposing the bone cells to viral infection.
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