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  • Title: Assessing a dysplastic cerebellar gangliocytoma (Lhermitte-Duclos disease) with 7T MR imaging.
    Author: Moenninghoff C, Kraff O, Schlamann M, Ladd ME, Katsarava Z, Gizewski ER.
    Journal: Korean J Radiol; 2010; 11(2):244-8. PubMed ID: 20191074.
    Abstract:
    Lhermitte-Duclos disease (LDD; dysplastic cerebellar gangliocytoma) is a rare hamartomatous lesion of the cerebellar cortex and this was first described in 1920. LDD is considered to be part of the autosomal-dominant phacomatosis and cancer syndrome Cowden disease (CS). We examined the brain of a 46-year-old man, who displayed the manifestations of CS, with 7 Tesla (T) and 1.5 T MRI and 1.5 T MR spectroscopy (1H-MRS). We discuss the possible benefits of employing ultrahigh-field MRI for making the diagnosis of this rare lesion.
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