These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Maternal plasma plasminogen activator inhibitor-2 at 11 to 13 weeks of gestation in hypertensive disorders of pregnancy.
    Author: Akolekar R, Cruz Jde J, Penco JM, Zhou Y, Nicolaides KH.
    Journal: Hypertens Pregnancy; 2011; 30(2):194-202. PubMed ID: 20205627.
    Abstract:
    OBJECTIVE: In patients with preeclampsia maternal plasma concentration of plasminogen activator inhibitor-2 (PAI-2) is reduced. The objective of the study was to determine if the altered levels of PAI-2 precede the onset of the disease. METHODS: Plasma PAI-2 was measured at 11-13 weeks of gestation in 119 pregnancies that developed preeclampsia, 85 that developed gestational hypertension and 204 controls. RESULTS: There were no significant differences in PAI-2 between the preeclampsia, gestational hypertension and controls (1.07 MoM, 1.08 MoM and 0.96 MoM). CONCLUSION: The decrease in plasma PAI-2 observed in preeclampsia does not precede the clinical onset of the disease.
    [Abstract] [Full Text] [Related] [New Search]