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  • Title: Epidermal laser stimulation of action potentials in the frog sciatic nerve.
    Author: Jindra NM, Goddard D, Imholte M, Thomas RJ.
    Journal: J Biomed Opt; 2010; 15(1):015002. PubMed ID: 20210442.
    Abstract:
    Measurements of laser-stimulated action potentials in the sciatic nerve of leopard frogs (Rana pipiens) are made using two infrared lasers. The dorsal sides of the frog's hind limbs are exposed to short-pulsed 1540- and 1064-nm wavelengths at three separate spot sizes: 2, 3, and 4 mm. Energy density thresholds are determined for eliciting an action potential at each experimental condition. Results from these exposures show similar evoked potential thresholds for both wavelengths. The 2-mm-diam spot sizes yield action potentials at radiant exposure levels almost double that seen with larger beam sizes.
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