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  • Title: [Studies on flavonoids and their antioxidant activities of Artemisia annua].
    Author: Yang GE, Bao L, Zhang XQ, Wang Y, Li Q, Zhang WK, Ye WC.
    Journal: Zhong Yao Cai; 2009 Nov; 32(11):1683-6. PubMed ID: 20218288.
    Abstract:
    OBJECTIVE: To study the flavonoids and their antioxidant activities of Artemisia annua. METHODS: Isolation and purification were carried out by silica gel and Sephadex LH-20 column chromatographies. Compounds were identified by physicochemical properties and spectral analysis, then their antioxidant activities were evaluated by ORAC assay. RESULTS: Five flavonoids were isolated from the plant. Their structures were identified as 5-hydroxy-3,7,4'-trimethoxyflavone(1), 5-hydroxy-6,7,3',4'-tetramethoxyflavonol(2), blumeatin(3), 5, 4'-dihydroxy-3,7,3'-trimethoxyflavone(4) and quercetin(5), respectively. Compounds 1-5 could slow up the attenuation rate of the fluorescence induced by AAPH. CONCLUSION: Compounds 1-3 are isolated from the plant for the first time. Compounds 1-5 all possess the potential antioxidant activities.
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