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  • Title: Computed tomography findings in radiation-induced osteosarcoma of the jaws.
    Author: Shao Z, He Y, Wang L, Hu H, Shi H.
    Journal: Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2010 Mar; 109(3):e88-94. PubMed ID: 20219593.
    Abstract:
    OBJECTIVE: The objective of this study was to report the CT appearances of radiation-induced jaw osteosarcomas (RIJOS) following therapeutic irradiation. STUDY DESIGN: The CT studies of 7 subjects with RIJOS were reviewed retrospectively. RESULTS: RIJOS developed at 3 to 14 years following radiotherapy. Four patients had tumors in the maxilla and 3 in the mandible. Five tumors were osteoblastic, with 1 osteolytic and 1 mixed lesions. Osteoid tumor matrix mineralization was identified in 6 subjects. Periosteal reaction was demonstrated in 6 cases. All subjects showed a soft tissue extension component beyond the area of bone destruction. CONCLUSION: CT is a useful tool to identify RIJOS and plays an important role in preoperative assessment of the extent of the tumor.
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