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  • Title: A new protocol in photodynamic therapy: enhanced tumour cell death by combining two different photosensitizers.
    Author: Villanueva A, Stockert JC, Cañete M, Acedo P.
    Journal: Photochem Photobiol Sci; 2010 Mar; 9(3):295-7. PubMed ID: 20221454.
    Abstract:
    The combined application of two photosensitisers (PSs), zinc(II) phthalocyanine (ZnPc) and the cationic porphyrin meso-tetrakis(4-N-methylpyridyl)porphine (T4MPyP), on HeLa cells produced an enhanced lethal effect relative to treatments with single PSs. Thus, the proper combination of PSs may constitute a new strategy to improve the efficacy of clinical photodynamic therapy.
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