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  • Title: Mechanisms of carbapenem resistance among a collection of Enterobacteriaceae clinical isolates in a Texas city.
    Author: Bennett JW, Mende K, Herrera ML, Yu X, Lewis JS, Wickes BL, Jorgensen JH, Murray CK.
    Journal: Diagn Microbiol Infect Dis; 2010 Apr; 66(4):445-8. PubMed ID: 20226336.
    Abstract:
    Fourteen Enterobacteriaceae isolates with ertapenem MIC >2 mg/mL were analyzed to identify mechanisms of resistance. All isolates produced extended-spectrum beta-lactamase or AmpC beta-lactamase with variable, but decreased, expression of outer membrane proteins. One Enterobacter cloacae produced derepressed AmpC beta-lactamase, 1 Escherichia coli expressed plasmid-mediated AmpC beta-lactamase, and 1 E. cloacae produced a carbapenemase.
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