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  • Title: Novel phenolic glycosides, adenophorasides A-E, from Adenophora roots.
    Author: Koike Y, Fukumura M, Hirai Y, Hori Y, Usui S, Atsumi T, Toriizuka K.
    Journal: J Nat Med; 2010 Jul; 64(3):245-51. PubMed ID: 20229365.
    Abstract:
    Five novel phenolic glycosides, adenophorasides A (1), B (2), C (3), D (4), and E (5), were isolated from commercial Adenophora roots, together with vanilloloside (6), 3,4-dimethoxybenzyl alcohol 7-O-beta-D: -glucopyranoside (7), and lobetyolin (8). The structures of the new compounds (1-5) were characterized as 4-hydroxy-3-methoxyphenylacetonitrile 4-O-beta-D: -glucopyranoside (1), 4-hydroxy-3-methoxyphenylacetonitrile 4-O-beta-D: -glucopyranosyl-(1-->6)-beta-D: -glucopyranoside (2), 4-hydroxy-3-methoxyphenylacetonitrile 4-O-alpha-L: -rhamnopyranosyl-(1-->6)-beta-D: -glucopyranoside (3), 4-hydroxyphenylacetonitrile 4-O-beta-D: -glucopyranosyl-(1-->6)-beta-D: -glucopyranoside (4), and 4-hydroxy-3-methoxybenzyl alcohol 4-O-beta-D: -glucopyranosyl-(1-->6)-beta-D: -glucopyranoside (5), respectively, by means of spectroscopic and chemical analyses.
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