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Title: Gukulenins A and B, cytotoxic tetraterpenoids from the marine sponge Phorbas gukulensis. Author: Park SY, Choi H, Hwang H, Kang H, Rho JR. Journal: J Nat Prod; 2010 Apr 23; 73(4):734-7. PubMed ID: 20232859. Abstract: Gukulenins A (1) and B (2), both having an unprecedented skeleton with a bis-tropolone moiety, were isolated from the Korean marine sponge Phorbas gukulensis. They exhibited significant cytotoxicity against human pharynx, stomach, colon, and renal cancer cell lines in the range 0.05-0.80 microM.[Abstract] [Full Text] [Related] [New Search]