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  • Title: [Prognosis and differential diagnosis of protracted pneumonia using the indicators of inhibition of proteolytic activity].
    Author: Provotorov VM, Semenkova GG.
    Journal: Klin Med (Mosk); 1991 Jan; 69(1):91-4. PubMed ID: 2023410.
    Abstract:
    Ninety-eight patients with protracted pneumonia were examined for activity of the system proteinases--proteinases inhibitors in bronchial secretion. Correlation between antitrypsin activity (ATA) and activity of trypsin-like proteinases (TLP) was most demonstrable. By calculating the ratio ATA/TLP the index of inhibition of proteolytic activity was derived applied in diagnosis of protracted and chronic pneumonias. ++Clinico-biochemical parallels obtained in patients with protracted pneumonia upon 1.5-year follow-up led the authors to conclusion that if the above index remains low for 1 month of the adequate therapy protracted pneumonia tends to chronicity. If the follow-up results are indicative of increasing index, pneumonia may terminate in recovery.
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