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  • Title: Cross-protective immunity and the serological classification system for Bacteroides nodosus.
    Author: Stewart DJ, Vaughan JA, Elleman TC, Hoyne PA, Burns KJ, Dufty JH.
    Journal: Aust Vet J; 1991 Feb; 68(2):50-3. PubMed ID: 2025201.
    Abstract:
    The relationship between the serological classification system for serogroup B and for serogroup H of Bacteroides nodosus and cross-protection between subgroups within these serogroups was examined. Protection against ovine footrot following vaccination was achieved against other subgroup strains provided sufficient cross-reactive antibody was induced by shared pilus antigens. Within serogroup B, better cross-protection against one subgroup was obtained with a pili vaccine than a whole cell vaccine which correlated with higher pilus antibody titres induced by the former. For serogroup H, a lack of cross-protection and serological reactivity between subgroups was demonstrated, which indicates that the prototype strain of subgroup H2 should be designated a new serogroup.
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