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Title: [Respiratory gas exchange during breathing of O2 in different inert gases (author's transl)]. Author: Grimrath U, Smidt U, von Nieding G, Krekeler H. Journal: Respiration; 1978; 35(1):14-21. PubMed ID: 203010. Abstract: In 15 patients with chronic bronchitis with or without emphysema breathing of room air was compared with breathing of 20.9% O2 in helium and in argon. Minute ventilation and alveolar ventilation showed no differences, whereas the alveolar and arterial pO2 and PCO2 showed an improvement of the CO2 gas exchange and a deterioration of the O2 gas exchange. This contradictory behaviour cannot be explained by shunts or inhomogeneities or influence of gaseous or alveolo-capillary diffusion. Perhaps the physicochemical properties of the alveolo-capillary membrane change by the depletion of nitrogen. The recommendation of helium-oxygen breathing, proposed by other authors for patients with obstructive airway diseases, cannot be supported, when the gas exchange for O2 is deteriorated.[Abstract] [Full Text] [Related] [New Search]