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  • Title: Australian Rotavirus Surveillance Program annual report, 2008/2009.
    Author: Kirkwood CD, Boniface K, Bishop RF, Barnes GL, Australian Rotavirus Surveillance Group.
    Journal: Commun Dis Intell Q Rep; 2009 Dec; 33(4):382-8. PubMed ID: 20301967.
    Abstract:
    The Australian Rotavirus Surveillance Program together with collaborating laboratories Australia-wide, conducts a laboratory based rotavirus surveillance program. This report describes the genotypes of rotavirus strains responsible for the hospitalisation of children with acute gastroenteritis during the period 1 July 2008 to 30 June 2009, the second year of surveillance following introduction of rotavirus vaccine into the National Immunisation Program. Five hundred and ninety-two faecal samples from across Australia were examined for G and P genotype using hemi-nested multiplex reverse transcription-polymerase chain reaction assays. Of the 445 confirmed as rotavirus positive, genotype G2P[4] was the dominant type nationally, representing 50.3%, followed by genotype G1P[8] (22.5%). Genotypes G3P[8], G4P[8] and G9P[8] each represented less than 5% of circulating strains nationally. Uncommon rotavirus genotype combinations, including G1P[4] (n = 6), G4P[4] (n = 2) and single strains of G1P[6] and G3P[6] were identified during this study period. The national dominance of G2P[4] was associated with a large outbreak of severe gastroenteritis in Alice Springs in early 2009. This is the first report to describe G2P[4] as the dominant genotype nationally. Whether vaccine pressure has resulted in emergence of this genotype is not yet known.
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