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  • Title: [An epidemiological survey of acute lymphocytic leukemia from 2002 to 2006 in Shanghai.].
    Author: Ni X, Shen ZX, Chen FY, Liang H, Tang JY, Lu FJ, Wang C, Shao JB, Hou J, Zou SH, Wang JM.
    Journal: Zhonghua Xue Ye Xue Za Zhi; 2010 Jan; 31(1):21-4. PubMed ID: 20302772.
    Abstract:
    OBJECTIVE: To analyse the epidemiological data of acute lymphoblastic leukemia (ALL) in Shanghai. METHODS: ALL cases in Shanghai from 2002 to 2006 were retrospectively investigated. RESULTS: All together there were 544 newly diagnozed ALL cases. The yearly incidence of ALL was 0.81/10(5), which was slightly higher in men (0.86/10(5)) than in women (0.75/10(5)). The age-stratified incidence showed 2.31/10(5) in patients (pts) </= 17y, 0.54/10(5) in 18 - 34 y, 0.46/10(5) in 35 - 59 y, and 0.94/10(5) in pts > 60 y. The incidences in Chongming County was 0.60/10(5), being the lowest in all districts. The morphological types of ALL was L(1) (26.2%), L(2) (57.4%) and L(3) (16.4%); the immunophenotype was B (80.1%) and T (19.5%). The incidence of ALL with myeloid antigen expression was 20.2%. Genetic examination revealed that chromosome aberration of t(9;22) was the most common one. CONCLUSIONS: The incidence of ALL in Shanghai is 0.81/10(5). Compared with the national standard (1986 - 1998), the incidence in adolescents is obviously increased. Chongming County has the lowest incidence, indicating a role of environment factor in ALL incidence.
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