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  • Title: Aspiration cytology of mesenchymal hamartoma of the chest wall in an infant: a case report.
    Author: Mathur SR, Gupta R, Seith A, Agarwala S, Subramanian S, Gupta SD.
    Journal: Acta Cytol; 2010; 54(1):63-5. PubMed ID: 20306991.
    Abstract:
    BACKGROUND: Mesenchymal hamartoma of the chest wall is an extremely uncommon lesion of infants. Radiologic features simulate a malignant neoplasm; however, pathologic examination demonstrates an admixture of fibroblasts, benign cartilage and woven bone. There is a paucity of cytologic reports of this rare entity in the available literature. CASE: A 5-month-old infant presented with a large right chest wall swelling. Radiologic investigation demonstrated lytic destruction of the right 7th, 8th and 9th ribs with a large soft tissue mass. Fine needle aspiration smears showed lobules of hyaline cartilage and a few spindle cells with abundant chondromyxoid matrix. A cytologic diagnosis of a benign chondroid, possibly hamartomatous lesion was given, which was confirmed as mesenchymal hamartoma on histopathologic examination. CONCLUSION: Mesenchymal hamartoma is a rare chest wall lesion that can be diagnosed on cytology, provided that the cytopathologist is aware of this uncommon entity and appreciates the benign cytologic features.
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