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  • Title: Comparison of salivary cortisol and calculated free plasma cortisol during low-dose ACTH test in healthy subjects.
    Author: Kerlik J, Penesova A, Vlcek M, Imrich R, Vogeser M, Radikova Z.
    Journal: Clin Biochem; 2010 Jun; 43(9):764-7. PubMed ID: 20307523.
    Abstract:
    OBJECTIVES: To compare free plasma cortisol (FPC) with salivary and calculated cortisol. DESIGN AND METHODS: FPC, salivary cortisol, free cortisol index (FCI), albumin-derived free cortisol index (FCIalb), Coolen's and Dorin's cortisol were assayed during repeated low-dose ACTH test in healthy women. RESULTS: FPC significantly correlated with its surrogates, the most with FCIalb and salivary cortisol. FPC and salivary cortisol showed the highest method agreement. CONCLUSIONS: FCIalb and salivary cortisol are preferred surrogates of FPC.
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