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  • Title: [The prevention of the hypercoagulation syndrome during the combined treatment of lung cancer patients using artificial hyperglycemia].
    Author: Fradkin SZ, Zhavrid EA, Prokhorova VI, Nodel'son SE, Khodina TV, Antipova LI, Demidchik IuE.
    Journal: Vopr Onkol; 1991; 37(3):321-9. PubMed ID: 2031327.
    Abstract:
    Status of hemostasis system and occurrence of postoperative thromboembolic complications were assessed in 246 lung cancer patients in whom combined treatment included artificial hyperglycemia. The latter condition contributed to higher blood coagulability resulting in lung artery thromboembolism in some cases. Administration of a combination of heparin, curantil and nicotinic acid was followed by a decrease in blood coagulability, increase in anticoagulation function, decrease in platelet aggregability, activation of fibrinolysis and regression of biochemical signs of DIC syndrome thereby assuring a drop in the occurrence of thromboembolic complications.
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