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  • Title: The beta-adrenergic activity of some monosubstituted phenethanolamines.
    Author: Letts LG, Easson PA, Temple DM, Lap BV, Lim CH, Orr AJ, Pasaribu SJ, Quessy SN, Williams LR.
    Journal: Arch Int Pharmacodyn Ther; 1977 Nov; 230(1):42-52. PubMed ID: 203235.
    Abstract:
    A series of monosubstituted phenethanolamines with N-isopropyl and N-tert-butyl substituents has been prepared. A detailed pharmacological study has been made of the beta-adrenergic activity of these materials as the nitrogen substituent and the nature and position of the phenyl substituent were changed, and their selectivity has been determined for beta1- and beta2-adrenoceptors in guinea-pig and cat tissues.
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