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  • Title: The alternate respiratory pathway of Candida albicans.
    Author: Shepherd MG, Chin CM, Sullivan PA.
    Journal: Arch Microbiol; 1978 Jan 23; 116(1):61-7. PubMed ID: 203238.
    Abstract:
    Candida albicans contains a cryptic cyanide and antimycin A insensitive respiratory system. This alternate oxidase was found (i) at all growth rates from mu = 0.05 to 0.26 in a chemostat culture and (ii) in both mycelial and yeast forms of the organism. Neither chloramphenicol nor cycloheximide prevented the expression of the alternate oxidase. Salicylhydroxamic acid was a potent inhibitor of the cyanide insensitive respiration. The respiration of mitochondria grown in the presence of antimycin A was not inhibited by cyanide or antimycin A but was inhibited by salicylhydroxamic acid.
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